Description

6-Bromo-4-Fluorobenzo[B]Thiophene-2-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which incorporates bromine and fluorine substituents on a benzo[b]thiophene carboxylic acid scaffold, enabling precise structural modifications. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it serves as a critical precursor for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated benzo[b]thiophene core.
• Material Science Research: Serves as a building block for organic electronic materials, such as semiconductors and light-emitting diodes (OLEDs).
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological processes due to its derivatizable carboxylic acid group.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring complex, halogenated heterocyclic structures.

Basic Information

Product Name	6-Bromo-4-Fluorobenzo[B]Thiophene-2-Carboxylic Acid
CAS No.	826995-57-7
Molecular Formula	C9H4BrFO2S
Molecular Weight	275.09 g/mol
Synonyms	6-Bromo-4-fluorobenzo[b]thiophene-2-carboxylic acid; 2-Benzo[b]thiophenecarboxylic acid, 6-bromo-4-fluoro-; 6-Bromo-4-fluoro-1-benzothiophene-2-carboxylic acid; 6-Bromo-4-fluorobenzothiophene-2-carboxylic acid; 826995-57-7; 6-Br-4-F-BT-2-COOH; 4-Fluoro-6-bromobenzo[b]thiophene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-4-Fluorobenzo[B]Thiophene-2-Carboxylic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical characterization. Our products are tested to ensure high chemical purity and structural integrity, meeting the exacting standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity (typically ≥95% by HPLC), and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled with appropriate precautions for strong acids/organic solvents. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.