Description

5-Fluoro-2-Thiophenemethanol is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its versatile thiophene scaffold and reactive hydroxymethyl group, which serve as key handles for constructing complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom and thiophene ring can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers, conductive materials, and liquid crystals.
• Organic Electronic Materials: Employed in the development of organic semiconductors, OLEDs, and photovoltaic materials due to the electron-rich nature of the thiophene ring.
• Chemical Research & Development: A versatile building block for constructing complex heterocyclic compounds and fluorinated analogs in academic and industrial R&D settings.
• Ligand and Catalyst Development: Useful for synthesizing novel chiral ligands or metal-organic frameworks (MOFs) for asymmetric catalysis and separation sciences.

Basic Information

Product Name	5-Fluoro-2-Thiophenemethanol
CAS No.	824983-56-4
Molecular Formula	C5H5FOS
Molecular Weight	132.16 g/mol
Synonyms	(5-Fluorothiophen-2-yl)methanol; 2-(Hydroxymethyl)-5-fluorothiophene; 5-Fluorothiophene-2-methanol; 5-Fluoro-2-thienylmethanol; 5-Fluoro-2-thiophenecarbinol; 5-Fluoro-thiophene-2-yl-methanol; 5-Fluoro-2-thienylcarbinol
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Thiophenemethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.