Description

2-Cyclopropyl-4-Iodo-1-Isopropyl-1H-Imidazole is a high-value, functionalized imidazole derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring cyclopropyl and iodo substituents, makes it an essential intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily sought after by R&D chemists and process development scientists working on novel active ingredients, particularly in medicinal chemistry for hit-to-lead optimization and the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Research: Used in the development of new fungicides, herbicides, and insecticides, leveraging the bioactivity of the imidazole core.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands in catalysis and materials science.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme mechanisms and biological pathways due to its halogenated structure.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to introduce the imidazole moiety into more complex architectures.
• Custom Synthesis & Contract Manufacturing: A vital component for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	2-Cyclopropyl-4-Iodo-1-Isopropyl-1H-Imidazole
CAS No.	824431-88-1
Molecular Formula	C9H13IN2
Molecular Weight	276.12 g/mol
Synonyms	4-Iodo-2-cyclopropyl-1-isopropyl-1H-imidazole; 1H-Imidazole, 2-cyclopropyl-4-iodo-1-(1-methylethyl)-; 2-Cyclopropyl-4-iodo-1-(propan-2-yl)-1H-imidazole; 1-Isopropyl-2-cyclopropyl-4-iodoimidazole; 4-Iodo-1-isopropyl-2-cyclopropylimidazole
EINECS	Contact for details

Quality Control

Every batch of 2-Cyclopropyl-4-Iodo-1-Isopropyl-1H-Imidazole is manufactured and tested under strict quality management systems to ensure consistency and reliability for your critical research and development processes. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.