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6-(4-Bromo-Phenyl)-5-Piperazin-1-Ylmethyl-Imidazo-[2,1-B]Thiazole CAS NO 824413-87-8


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CAS No.:824413-87-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-(4-Bromo-Phenyl)-5-Piperazin-1-Ylmethyl-Imidazo-[2,1-B]Thiazole is a high-purity, advanced pharmaceutical intermediate of significant interest in modern drug discovery. This compound matters for its role as a key building block in the synthesis of novel bioactive molecules, particularly in the development of kinase inhibitors and other targeted therapies. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material to support their programs in oncology and central nervous system (CNS) research.

Application

  • Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates, especially kinase inhibitors.
  • Biochemical Research: Used as a reference standard or a tool compound in pharmacological and biological screening assays.
  • Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
  • Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
  • Academic Research: Utilized in university and institutional labs for investigating new heterocyclic chemistry and biological pathways.

Basic Information

Product Name 6-(4-Bromo-Phenyl)-5-Piperazin-1-Ylmethyl-Imidazo-[2,1-B]Thiazole
CAS No. 824413-87-8
Molecular Formula C17H19BrN4S
Molecular Weight 391.33 g/mol
Synonyms 6-(4-Bromophenyl)-5-[(piperazin-1-yl)methyl]imidazo[2,1-b][1,3]thiazole; 5-(Piperazin-1-ylmethyl)-6-(4-bromophenyl)imidazo[2,1-b]thiazole; Imidazo[2,1-b]thiazole, 6-(4-bromophenyl)-5-(1-piperazinylmethyl)-; 824413-87-8; 6-(p-Bromophenyl)-5-piperazin-1-ylmethylimidazo[2,1-b]thiazole
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Quality Control

Our 6-(4-Bromo-Phenyl)-5-Piperazin-1-Ylmethyl-Imidazo-[2,1-B]Thiazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item Specification
Appearance White to off-white solid
Identification (HPLC) Conforms
Identification (IR) Conforms
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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