Description

Thiazole, 2-[(4,4-Difluoro-3-Butenyl)Thio]-4,5-Dihydro-4-Methyl-, (4R)- (9Ci) is a specialized chiral thiazole derivative of significant interest in advanced organic synthesis. This compound matters as a high-value building block, offering a unique combination of a fluorinated side chain and a stereogenic center for creating complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for introducing fluorinated motifs.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where the thiazole core and fluorine atoms contribute to biological activity.
• Chemical Research: Acts as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of complex target molecules.
• Material Science Precursor: Potential use in the synthesis of specialized ligands or functionalized materials.

Basic Information

Product Name	Thiazole, 2-[(4,4-Difluoro-3-Butenyl)Thio]-4,5-Dihydro-4-Methyl-, (4R)- (9Ci)
CAS No.	824391-26-6
Molecular Formula	C9H13F2NS2
Molecular Weight	237.33 g/mol
Synonyms	(4R)-2-[(4,4-Difluoro-3-buten-1-yl)thio]-4-methyl-4,5-dihydrothiazole; 2-[(4,4-Difluoro-3-butenyl)thio]-4,5-dihydro-4-methyl-, (4R)-Thiazole; (R)-2-((4,4-Difluorobut-3-en-1-yl)thio)-4-methyl-4,5-dihydrothiazole; 824391-26-6; (4R)-4-Methyl-2-[(4,4-difluorobut-3-en-1-yl)sulfanyl]-4,5-dihydro-1,3-thiazole
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥97% (by HPLC), with specifications tailored for research and development use. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong alkalis and fluorides. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.