Description

1H-Indazole-1-Carboxylic Acid,6-Formyl-,1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its indazole core and formyl-protecting group. This compound is critical for research and development in medicinal chemistry, particularly for constructing complex molecular architectures. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and bioactive compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes.
• Organic Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of diverse chemical libraries.
• API Development: Integral to the development and scale-up processes for new active pharmaceutical ingredients.
• Biochemical Research: Potential use in the development of enzyme inhibitors or receptor modulators due to its heterocyclic structure.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals for advanced applications.

Basic Information

Product Name	1H-Indazole-1-Carboxylic Acid,6-Formyl-,1,1-Dimethylethyl Ester
CAS No.	821767-62-8
Molecular Formula	C14H16N2O3
Molecular Weight	260.29 g/mol
Synonyms	tert-Butyl 6-formyl-1H-indazole-1-carboxylate; 6-Formyl-1H-indazole-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-6-formyl-1H-indazole; 1-Boc-6-formyl-1H-indazole; Boc-6-formylindazole; tert-Butyl 6-formylindazole-1-carboxylate; 1H-Indazole-1-carboxylic acid, 6-formyl-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 1H-Indazole-1-Carboxylic Acid,6-Formyl-,1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C for long-term stability. The material should be kept under inert atmosphere if specified. Allow the container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.