Description

3-Methanesulfonylacetylindole is a high-purity, advanced pharmaceutical intermediate characterized by its unique indole core functionalized with a methanesulfonylacetyl group. This compound is of significant value in modern organic synthesis, particularly for constructing complex molecular architectures in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Organic Synthesis Reagent: Serves as a versatile precursor for introducing the methanesulfonylacetyl moiety into more complex heterocyclic systems.
• Biochemical Research: Potential use as a probe or inhibitor in enzymatic studies due to its specific structural features.
• Fine Chemical Production: Employed in the multi-step synthesis of specialized, high-value chemical products.

Basic Information

Product Name	3-Methanesulfonylacetylindole
CAS No.	821009-91-0
Molecular Formula	C11H11NO3S
Molecular Weight	237.28 g/mol
Synonyms	1H-Indole-3-acetic acid, 2-(methylsulfonyl)-; 2-(Methylsulfonyl)-1H-indole-3-acetic acid; 3-(2-Methanesulfonylacetyl)indole; 3-(Methanesulfonylacetyl)-1H-indole; 3-Methanesulfonylacetyl-1H-indole; 1H-Indole-3-glyoxylic acid, 2-(methylsulfonyl)-; 3-(Methylsulfonylacetyl)indole
EINECS	Contact for details

Quality Control

Our 3-Methanesulfonylacetylindole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.