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Cyclohexanol, 5-Methyl-2-[(4R)-2,2,4-Trimethyl-1,3-Dioxolan-4-Yl]-, (1R,2R,5R)- (9Ci) CAS NO 820208-73-9


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CAS No.:820208-73-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Cyclohexanol, 5-Methyl-2-[(4R)-2,2,4-Trimethyl-1,3-Dioxolan-4-Yl]-, (1R,2R,5R)- (9Ci) is a high-purity, stereochemically defined chiral intermediate of significant importance in advanced organic synthesis. Its value lies in its complex, rigid structure which serves as a sophisticated building block for the creation of biologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, flavors, and fragrances, where precise stereochemistry is critical for function.

Application

  • Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for complex target molecules.
  • Asymmetric Synthesis: Employed as a building block in stereoselective reactions to construct complex natural products and other chiral compounds.
  • Flavor & Fragrance (F&F) Industry: Used in the synthesis of high-value aroma chemicals where specific stereoisomers impart unique sensory properties.
  • Agrochemical Research: Serves as an intermediate in the development of new, stereospecific pesticides and herbicides.
  • Material Science: Potential use in the synthesis of specialized monomers for advanced polymers with specific optical or mechanical properties.
  • Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and catalysis within university and CRO laboratories.

Basic Information

Product Name Cyclohexanol, 5-Methyl-2-[(4R)-2,2,4-Trimethyl-1,3-Dioxolan-4-Yl]-, (1R,2R,5R)- (9Ci)
CAS No. 820208-73-9
Molecular Formula C13H24O3
Molecular Weight 228.33 g/mol
Synonyms (1R,2R,5R)-5-Methyl-2-[(4R)-2,2,4-Trimethyl-1,3-Dioxolan-4-yl]cyclohexanol; (1R,2R,5R)-5-Methyl-2-((4R)-2,2,4-trimethyl-1,3-dioxolan-4-yl)cyclohexan-1-ol; (-)-Menthol ketal derivative; (1R,2R,5R)-Isomer of the menthol acetonide; Chiral menthol acetonide; (1R,2R,5R,4'R)-Configured cyclohexanol dioxolane.
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Quality Control

Our production of this advanced chiral intermediate adheres to strict quality management systems. Each batch is characterized using advanced analytical techniques including Chiral HPLC, GC, and NMR to ensure stereochemical purity and chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profile is provided with every shipment, supporting your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound may be sensitive to moisture and should be handled under an inert atmosphere for long-term storage to maintain optimal purity.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Purity (GC/HPLC) ≥ 97.0%
Enantiomeric Excess (Chiral HPLC) ≥ 99.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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