Description

3-(4-Fluorophenyl)-5-Nitro-1H-Indazole is a high-purity, advanced pharmaceutical intermediate characterized by its unique indazole core functionalized with fluorophenyl and nitro groups. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its versatile chemical scaffold.
• Biochemical Tool Compound: Acts as a precursor or reference standard in the development of assays for biological target screening.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to introduce the 3-(4-fluorophenyl)-5-nitro-1H-indazole moiety into more complex molecular architectures.
• Academic Research: Utilized in university and institutional labs for exploratory research in heterocyclic chemistry and drug discovery methodologies.

Basic Information

Product Name	3-(4-Fluorophenyl)-5-Nitro-1H-Indazole
CAS No.	817200-27-4
Molecular Formula	C₁₃H₈FN₃O₂
Molecular Weight	257.22 g/mol
Synonyms	5-Nitro-3-(4-fluorophenyl)-1H-indazole; 1H-Indazole, 3-(4-fluorophenyl)-5-nitro-; 3-(p-Fluorophenyl)-5-nitro-1H-indazole; 817200-27-4; AKOS005258065; AS-64179; SCHEMBL2180626; ZINC000257830911
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorophenyl)-5-Nitro-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.