Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carboxaldehyde, 2-Methyl-3-Phenyl-, (1R,2S,3S,4S)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its complex, rigid bicyclic framework and defined stereochemistry make it a valuable precursor for constructing sophisticated molecular architectures with precise three-dimensional control. This compound is primarily sought after by pharmaceutical R&D and fine chemical sectors for applications in asymmetric catalysis and the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Asymmetric Synthesis: Serves as a sophisticated starting material or ligand precursor in catalytic asymmetric reactions to induce high enantioselectivity.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex natural products, fragrances, and specialty chemicals requiring a defined bicyclic core structure.
• Material Science Research: Potential monomer or cross-linking agent for developing polymers with unique thermal and mechanical properties derived from its strained norbornene skeleton.
• Agrochemical Development: Intermediate in the synthesis of advanced, stereospecific crop protection agents and pesticides.
• Academic & Industrial R&D: A valuable tool compound for methodological studies in organic chemistry and catalysis.

Basic Information

Item	Details
Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carboxaldehyde, 2-Methyl-3-Phenyl-, (1R,2S,3S,4S)- (9Ci)
CAS No.	816454-32-7
Molecular Formula	C15H16O
Molecular Weight	212.29 g/mol
Synonyms	(1R,2S,3S,4S)-2-Methyl-3-phenylbicyclo[2.2.1]hept-5-ene-2-carboxaldehyde; endo-2-Methyl-3-phenyl-5-norbornene-2-carboxaldehyde; 2-Methyl-3-phenyl-5-norbornene-2-carbaldehyde; (1R,2S,3S,4S)-2-Methyl-3-phenyl-5-norbornene-2-carboxaldehyde; 2-Methyl-3-phenylbicyclo[2.2.1]hept-5-ene-2-carbaldehyde; (1R,2S,3S,4S)-rel-2-Methyl-3-phenylbicyclo[2.2.1]hept-5-ene-2-carboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of our chiral intermediates is produced under strict quality management protocols. We employ advanced analytical techniques, including chiral HPLC, GC, and NMR, to ensure exceptional chemical and enantiomeric purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This compound is light-sensitive and easily oxidized; minimize exposure to air and light during handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.