Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carboxaldehyde, 2-Methyl-3-Phenyl-, (1R,2S,3S,4S)-Rel- (9Ci) is a high-purity, stereochemically defined chiral building block essential for advanced organic synthesis. This compound matters because its rigid norbornene framework and specific stereochemistry make it a valuable precursor for constructing complex molecules with precise three-dimensional architecture. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as asymmetric catalysis and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Asymmetric Catalyst Ligand Precursor: Used to synthesize novel, sterically demanding ligands for transition metal catalysts in enantioselective reactions.
• Agrochemical Synthesis: Employed in the creation of advanced, stereospecific pesticides and herbicides where the defined spatial orientation is critical for bioactivity.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or mechanical properties derived from the norbornene structure.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, including Diels-Alder reactions and other cycloadditions.
• Fine Chemical Production: Utilized in the custom synthesis of complex fragrance molecules and other high-value specialty chemicals.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carboxaldehyde, 2-Methyl-3-Phenyl-, (1R,2S,3S,4S)-Rel- (9Ci)
CAS No.	816454-13-4
Molecular Formula	C15H16O
Molecular Weight	212.29 g/mol
Synonyms	rel-(1R,2S,3S,4S)-2-Methyl-3-phenylbicyclo[2.2.1]hept-5-ene-2-carboxaldehyde; 2-Norbornene-2-carboxaldehyde, 2-methyl-3-phenyl-, (1R,2S,3S,4S)-rel-; (1R,2S,3S,4S)-rel-2-Methyl-3-phenyl-5-norbornene-2-carboxaldehyde; 2-Methyl-3-phenyl-5-norbornene-2-carboxaldehyde (rel-isomer); Bicyclo[2.2.1]hept-5-ene-2-carboxaldehyde, 2-methyl-3-phenyl-, (1R,2S,3S,4S)-rel-; Chiral Norbornene Aldehyde Derivative
EINECS	Contact for details

Quality Control

Every batch of this chiral aldehyde is produced and analyzed under strict quality management protocols to ensure identity, purity, and stereochemical integrity. Our standard grade typically meets a purity specification of ≥97% (by HPLC) with enantiomeric excess (ee) confirmed. Comprehensive testing includes identification (IR, NMR), assay (HPLC), and control of key impurities. Certificates of Analysis (COA) detailing all specifications and results are provided with each shipment. We support development projects and can discuss custom purity grades or analytical packages to meet specific research needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should be kept sealed under positive pressure of inert gas after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.