Description

3-Bromo-Thiophene-2-Carboxylic Acid Methylamide is a high-purity, functionalized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its versatile reactivity, where the bromine atom and the amide functionality serve as key handles for constructing complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the preparation of advanced crop protection agents, including herbicides and fungicides, leveraging the thiophene scaffold's bioactivity.
• Material Science Research: Serves as a precursor for the synthesis of functional polymers, organic semiconductors, and conductive materials due to the thiophene core.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for metal-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination.
• Chemical Biology Probes: Utilized as a building block for designing molecular probes to study biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector with tailored, complex molecules.

Basic Information

Product Name	3-Bromo-Thiophene-2-Carboxylic Acid Methylamide
CAS No.	816418-30-1
Molecular Formula	C7H6BrNOS
Molecular Weight	232.10 g/mol
Synonyms	3-Bromo-2-(methylcarbamoyl)thiophene; Methyl 3-bromothiophene-2-carboxamide; N-Methyl-3-bromothiophene-2-carboxamide; 3-Bromo-N-methylthiophene-2-carboxamide; 2-Thiophenecarboxamide, 3-bromo-N-methyl-; 816418-30-1; 3-Bromo-thiophene-2-carboxylic acid methyl amide
EINECS	Contact for details

Quality Control

Our 3-Bromo-Thiophene-2-Carboxylic Acid Methylamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.