Description

2-Thiophenecarboxamide, 5-Chloro-n-[(1R)-1-(Methoxymethyl)-2-[[3-Methyl-4-(3-Oxo-4-Morpholinyl)Phenyl]Amino]-2-Oxoethyl]- is a high-purity, advanced pharmaceutical intermediate with a complex, chiral molecular structure. This compound is of significant value in the research and development of novel therapeutic agents, particularly as a key building block in medicinal chemistry. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the multi-step synthesis of potential active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a scaffold or precursor in drug discovery programs for structure-activity relationship (SAR) studies.
• Protease Inhibitor Development: Its structural motifs suggest potential application in the design of inhibitors targeting specific enzymatic pathways.
• Kinase Inhibitor Synthesis: May be utilized in the development of kinase-targeted therapies for oncology and inflammatory diseases.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic & Institutional Research: Used in university and institutional labs for advanced chemical and pharmacological studies.

Basic Information

Product Name	2-Thiophenecarboxamide, 5-Chloro-n-[(1R)-1-(Methoxymethyl)-2-[[3-Methyl-4-(3-Oxo-4-Morpholinyl)Phenyl]Amino]-2-Oxoethyl]-
CAS No.	811811-33-3
Molecular Formula	C20H24ClN3O4S
Molecular Weight	437.94 g/mol
Synonyms	5-Chloro-N-[(1R)-1-(methoxymethyl)-2-[[3-methyl-4-(3-oxo-4-morpholinyl)phenyl]amino]-2-oxoethyl]-2-thiophenecarboxamide; (R)-5-Chloro-N-(1-(methoxymethyl)-2-((3-methyl-4-(3-oxomorpholino)phenyl)amino)-2-oxoethyl)thiophene-2-carboxamide; UNII-4K8J0W4W8I; 4K8J0W4W8I; Thiophene-2-carboxamide, 5-chloro-N-[(1R)-1-(methoxymethyl)-2-[[3-methyl-4-(3-oxo-4-morpholinyl)phenyl]amino]-2-oxoethyl]-; A potential metabolite or derivative of related kinase inhibitors.
EINECS	Contact for details

Quality Control

This product is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity, suitable for demanding research applications. Our quality system emphasizes identity confirmation, purity assessment, and impurity profiling. Certificates of Analysis (COA) detailing specific tests and results, including chiral purity, are provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.