Description

3-(2,4-Dimethylphenyl)-2-Sulfanylidene-1H,2H,3H,4H-Thieno[3,2-D]Pyrimidin-4-One is a high-purity, advanced pharmaceutical intermediate belonging to the thienopyrimidinone class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities, particularly in oncology and antiviral drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new pharmacophores.
• Organic Synthesis Building Block: Serves as a versatile scaffold for constructing complex heterocyclic systems in academic and industrial R&D laboratories.
• Biochemical Tool Compound: Potential use in biochemical assays to study enzyme inhibition and cellular signaling pathways.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP-scale production of clinical trial materials.

Basic Information

Product Name	3-(2,4-Dimethylphenyl)-2-Sulfanylidene-1H,2H,3H,4H-Thieno[3,2-D]Pyrimidin-4-One
CAS No.	811451-04-4
Molecular Formula	C15H14N2OS2
Molecular Weight	302.41 g/mol
Synonyms	3-(2,4-Dimethylphenyl)-2-thioxo-2,3-dihydro-1H-thieno[3,2-d]pyrimidin-4(5H)-one; 2-Thioxo-3-(2,4-dimethylphenyl)-1,2,3,5-tetrahydro-4H-thieno[3,2-d]pyrimidin-4-one; Thieno[3,2-d]pyrimidin-4(5H)-one, 3-(2,4-dimethylphenyl)-2,3-dihydro-2-thioxo-; 811451-04-4; 3-(2,4-Dimethylphenyl)-2-sulfanyliden-1H,2H,3H,4H-thieno[3,2-d]pyrimidin-4-on
EINECS	Contact for details

Quality Control

Our 3-(2,4-Dimethylphenyl)-2-Sulfanylidene-1H,2H,3H,4H-Thieno[3,2-D]Pyrimidin-4-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed chromatographic data are provided with each shipment. We can support development with custom purity grades, including research-grade and cGMP-grade materials for advanced clinical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Research Grade)
Purity (HPLC)	≥ 98.0% (Advanced Grade)
Purity (HPLC)	≥ 99.0% (cGMP Grade)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.