Description

1H-Isoindole-1-Carboxylicacid,Octahydro-,(1S,3As,7As)-(9Ci) CAS NO 811420-48-1 is a high-purity, stereochemically defined bicyclic organic compound, serving as a critical chiral building block in advanced synthetic chemistry. Its value lies in its rigid, fused-ring structure and defined stereochemistry, which are essential for constructing complex molecules with precise three-dimensional architecture. This intermediate is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides requiring specific stereoisomers for optimal activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the development of novel chiral ligands and organocatalysts.
• Academic & Industrial R&D: Employed in methodological studies and process chemistry for constructing complex, polycyclic molecular frameworks.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals where the isoindole scaffold imparts desired physical or biological properties.

Basic Information

Product Name	1H-Isoindole-1-Carboxylicacid,Octahydro-,(1S,3As,7As)-(9Ci)
CAS No.	811420-48-1
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	(1S,3aS,7aS)-Octahydro-1H-isoindole-1-carboxylic acid; (1S,3aS,7aS)-1,2,3,3a,4,5,6,7a-Octahydroisoindole-1-carboxylic acid; (1S,3aS,7aS)-Octahydroisoindole-1-carboxylic acid; (1S,3aS,7aS)-Perhydroisoindole-1-carboxylic acid; (1S,3aS,7aS)-Hexahydro-1H-isoindole-1-carboxylic acid (ambiguous); Chiral Octahydroisoindolecarboxylic Acid; Stereoisomer of Octahydro-1H-isoindole-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1H-Isoindole-1-Carboxylicacid,Octahydro-,(1S,3As,7As)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed and under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.