Description

2-Oxa-3-Azabicyclo[2.2.2]Oct-5-Ene, 2,2,2-Trifluoroacetate is a specialized bicyclic organic compound that serves as a high-value synthetic intermediate and building block in advanced chemical synthesis. Its unique constrained molecular architecture and trifluoroacetate functional group make it a critical precursor for constructing complex pharmacophores and novel materials. This compound is primarily utilized by research institutions and industrial R&D departments focused on pharmaceuticals, agrochemicals, and advanced material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery programs.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its nitrogen-oxygen heterocyclic core.
• Ligand & Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Intermediate in the synthesis of specialty polymers and advanced organic frameworks with specific electronic or structural properties.
• Academic & Contract Research: Employed in methodological studies and the exploration of new synthetic pathways in organic chemistry.
• Fluorine Chemistry: The trifluoroacetate moiety provides a handle for introducing fluorine atoms into target molecules, a common strategy in medicinal chemistry to modulate bioavailability and metabolic stability.

Basic Information

Product Name	2-Oxa-3-Azabicyclo[2.2.2]Oct-5-Ene, 2,2,2-Trifluoroacetate
CAS No.	809288-09-3
Molecular Formula	C8H8F3NO3
Molecular Weight	223.15 g/mol
Synonyms	2,2,2-Trifluoroacetic Acid 2-Oxa-3-azabicyclo[2.2.2]oct-5-ene Ester; 3-Aza-2-oxabicyclo[2.2.2]oct-5-ene 2,2,2-Trifluoroacetate; Bicyclo[2.2.2]oct-5-ene-2,3-diol, 2-(trifluoroacetate), 3-imine; 2-Oxa-3-azabicyclo[2.2.2]oct-5-en-2-yl trifluoroacetate; Trifluoroacetic acid 2-oxa-3-azabicyclo[2.2.2]oct-5-en-2-yl ester; 809288-09-3; 2-Oxa-3-azabicyclo[2.2.2]oct-5-ene trifluoroacetate
EINECS	Contact for details

Quality Control

Our 2-Oxa-3-Azabicyclo[2.2.2]Oct-5-Ene, 2,2,2-Trifluoroacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and GC-MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support custom synthesis and can tailor purity grades (e.g., >95%, >98%, >99%) to meet specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.