Description

Bicyclo[4.1.0]Heptane-7-Acetamide, 1-(Hydroxymethyl)-N,N,6-Trimethyl-, (1R,6R,7S)-Rel- (9Ci) is a high-purity, stereochemically defined bicyclic acetamide derivative. This compound serves as a critical chiral building block and advanced intermediate in sophisticated organic synthesis. It is primarily required by pharmaceutical R&D and fine chemical sectors for developing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Synthesis: Utilized as a sophisticated scaffold or ligand precursor in catalytic asymmetric reactions to induce high enantioselectivity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization due to its constrained bicyclic framework and functional handles.
• Fine Chemical Production: Serves as a high-value intermediate for the custom synthesis of complex, specialty chemicals for agrochemical and material science applications.
• Academic & Industrial R&D: Used in methodological development and exploration of novel reaction pathways involving strained ring systems.

Basic Information

Product Name	Bicyclo[4.1.0]Heptane-7-Acetamide, 1-(Hydroxymethyl)-N,N,6-Trimethyl-, (1R,6R,7S)-Rel- (9Ci)
CAS No.	809237-28-3
Molecular Formula	C13H23NO2
Molecular Weight	225.33 g/mol
Synonyms	rel-(1R,6R,7S)-1-(Hydroxymethyl)-N,N,6-trimethylbicyclo[4.1.0]heptane-7-acetamide; 1-(Hydroxymethyl)-N,N,6-trimethylbicyclo[4.1.0]heptane-7-acetamide (rel-(1R,6R,7S)-); Bicyclo[4.1.0]heptane-7-acetamide, 1-(hydroxymethyl)-N,N,6-trimethyl-, (1R,6R,7S)-rel-; (1R,6R,7S)-rel-1-(Hydroxymethyl)-N,N,6-trimethylbicyclo[4.1.0]heptane-7-carboxamide; 809237-28-3; Chiral Bicyclo[4.1.0]heptane Acetamide Derivative
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including chiral purity verification by HPLC, to ensure consistent chemical and stereochemical integrity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data (HPLC, NMR, MS) are provided to support your R&D and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.