Description

4-(Chloromethyl)-5,7-Dihydroxy-2H-Chromen-2-One is a functionalized coumarin derivative, a versatile chemical scaffold of significant interest in advanced organic synthesis. This compound matters for its role as a key synthetic intermediate in the development of more complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), fluorescent probes, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of novel drug candidates, especially those targeting specific enzyme pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators that leverage the coumarin core structure.
• Fluorescent Dye & Probe Synthesis: Acts as a precursor for creating advanced fluorescent markers and molecular probes used in bioimaging and diagnostics.
• Organic Synthesis & Material Science: Employed in academic and industrial research to construct complex heterocyclic compounds or functional materials.
• Cosmetic Ingredient Research: Investigated for potential use in skincare formulations due to the bioactive properties of hydroxylated coumarins.

Basic Information

Product Name	4-(Chloromethyl)-5,7-Dihydroxy-2H-Chromen-2-One
CAS No.	809234-33-1
Molecular Formula	C10H7ClO4
Molecular Weight	226.61 g/mol
Synonyms	5,7-Dihydroxy-4-(chloromethyl)-2H-chromen-2-one; 4-(Chloromethyl)-5,7-dihydroxycoumarin; 5,7-Dihydroxy-4-(chloromethyl)coumarin; 4-Chloromethyl-5,7-dihydroxycoumarin; 5,7-Dihydroxy-4-chloromethylcoumarin; 4-(Chloromethyl)umbelliferone derivative; 809234-33-1 (CAS Index Name)
EINECS	Contact for details

Quality Control

Our 4-(Chloromethyl)-5,7-Dihydroxy-2H-Chromen-2-One is produced under strict quality management protocols. We offer material suitable for research and development purposes, with typical purity levels meeting the requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each batch to ensure traceability and support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.