Description

2-Benzyl-7-Chloro-3,4-Dihydroisoquinolin-1(2H)-One is a high-purity, synthetically valuable organic compound belonging to the dihydroisoquinolinone class. This compound serves as a critical pharmaceutical intermediate and a versatile building block in advanced organic synthesis, enabling the development of novel active molecules. It is primarily required by research institutions and pharmaceutical manufacturers engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential therapeutic agents, particularly in central nervous system (CNS) and oncology research.
• Organic Synthesis Building Block: Used for constructing complex heterocyclic frameworks due to its reactive dihydroisoquinolinone core.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs.
• Process Development: Serves as a standard or starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Chemical Reference Standard: Used for analytical method development, validation, and quality control in API manufacturing.
• Academic Research: Utilized in universities and institutes for studying novel synthetic methodologies and reaction mechanisms.

Basic Information

Item	Details
Product Name	2-Benzyl-7-Chloro-3,4-Dihydroisoquinolin-1(2H)-One
CAS No.	808141-26-6
Molecular Formula	C₁₆H₁₄ClNO
Molecular Weight	271.74 g/mol
Synonyms	7-Chloro-2-benzyl-1,2,3,4-tetrahydroisoquinolin-1-one; 2-Benzyl-7-chloro-3,4-dihydro-1(2H)-isoquinolinone; 7-Chloro-2-benzyl-3,4-dihydroisoquinolin-1(2H)-one; 808141-26-6; 2-Benzyl-7-chloro-1,2,3,4-tetrahydroisoquinolin-1-one; 7-Chloro-2-benzyl-1,2,3,4-tetrahydroisoquinoline-1-one
EINECS	Contact for details

Quality Control

Our 2-Benzyl-7-Chloro-3,4-Dihydroisoquinolin-1(2H)-One is manufactured under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.