Description

2H-Thieno[2,3-B]Indole,3,3A,8,8A-Tetrahydro-3A,8-Dimethyl-,(3Ar,8Ar)-Rel-(9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex fused-ring structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders.
• Organic Synthesis Building Block: Used in research-scale and pilot-scale organic reactions to construct novel heterocyclic compounds with potential biological activity.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies in academic and industrial drug discovery programs.
• Process Chemistry Development: Employed in the optimization and scale-up of synthetic routes for new chemical entities (NCEs).
• Reference Standard: Used as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	2H-Thieno[2,3-B]Indole,3,3A,8,8A-Tetrahydro-3A,8-Dimethyl-,(3Ar,8Ar)-Rel-(9Ci)
CAS No.	807648-95-9
Molecular Formula	C12H14S
Molecular Weight	190.30 g/mol
Synonyms	rel-(3aR,8aR)-3a,8-Dimethyl-2,3,3a,8-tetrahydrothieno[2,3-b]indole; (3aR,8aR)-3a,8-Dimethyl-3a,8a-dihydro-2H-thieno[2,3-b]indole; Tetrahydrothienoindole derivative; 2H-Thieno[2,3-b]indole, 3,3a,8,8a-tetrahydro-3a,8-dimethyl-, (3aR,8aR)-rel-; 807648-95-9; SCHEMBL21823027; A1-00826
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure structural identity and purity. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet client-specific requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed under an inert atmosphere to prevent degradation. This material is moisture-sensitive and should be handled in a dry environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.