Description

Nitrilotriacetic Acid-D9 is a deuterated analog of the well-known chelating agent nitrilotriacetic acid (NTA), specifically designed for advanced analytical and research applications. This high-purity, isotopically labeled compound is essential for use as an internal standard in mass spectrometry, enabling precise quantification and minimizing matrix effects. It is primarily utilized by analytical chemists and researchers in the pharmaceutical, environmental testing, and metabolomics sectors who require uncompromised accuracy and reliability in their trace metal analysis and complexation studies.

Application

• Internal Standard for LC/MS and GC/MS: Serves as a critical, non-interfering reference compound for the accurate quantification of NTA and related chelators in complex biological and environmental matrices.
• Metabolomics and Proteomics Research: Used in stable isotope labeling studies to track biochemical pathways and protein interactions with high specificity.
• Environmental Analysis: Enables precise measurement of NTA and its metal complexes in water and soil samples for environmental monitoring and regulatory compliance.
• Pharmaceutical R&D: Supports method development and validation in drug metabolism and pharmacokinetics (DMPK) studies where metal chelation is a factor.
• NMR Spectroscopy: Acts as a deuterated agent in nuclear magnetic resonance studies, providing a non-protonated background for clearer spectral analysis.
• Chemical Mechanism Studies: Facilitates detailed investigation of chelation kinetics and metal-binding mechanisms using isotopic tracing techniques.

Basic Information

Product Name	Nitrilotriacetic Acid-D9
CAS No.	807630-34-8
Molecular Formula	C6D9NO6
Molecular Weight	About 195.18 g/mol
Synonyms	NTA-d9; Tris(carboxymethyl)amine-d9; Deuterated Nitrilotriacetic Acid; 2,2',2''-Nitrilotriacetic-d9 acid; (Carboxymethyl-d2)iminodiacetic-2,2-d2 acid; Glycine, N,N-bis(carboxymethyl-d2)-; Aminotriacetic-d9 Acid; Trilon® A-d9 (analog)
EINECS	Contact for details

Quality Control

Every batch of Nitrilotriacetic Acid-D9 is produced and analyzed under strict quality management protocols to ensure exceptional isotopic purity and chemical integrity, critical for sensitive analytical applications. Our products undergo rigorous quality testing, including NMR and mass spectrometry, to confirm deuterium incorporation and chemical purity. A comprehensive Certificate of Analysis (COA) detailing isotopic purity, assay, and impurity profiles is provided with each shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed immediately after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Isotopic Purity (D-content)	≥ 98 atom % D
Assay (HPLC)	≥ 95%
Chemical Purity (HPLC)	≥ 98%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.