Description

5-Isoquinolinecarboxylic Acid, 1,2,3,4-Tetrahydro-4,6,7-Trihydroxy- (9Ci) is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique tetrahydroisoquinoline scaffold with multiple hydroxyl groups makes it a valuable precursor for developing complex molecules with potential biological activity. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for use in medicinal chemistry, process development, and as a key intermediate for novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its versatile functional groups.
• Agrochemical Synthesis: Acts as a precursor in the development of new herbicides, fungicides, or plant growth regulators.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms or cellular pathways.
• Ligand Synthesis for Catalysis: The hydroxyl and carboxylic acid functionalities make it suitable for constructing complex chelating ligands used in asymmetric catalysis.
• Advanced Material Precursor: Potential use in synthesizing organic components for electronic materials or metal-organic frameworks (MOFs).

Basic Information

Product Name	5-Isoquinolinecarboxylic Acid, 1,2,3,4-Tetrahydro-4,6,7-Trihydroxy- (9Ci)
CAS No.	807262-08-4
Molecular Formula	C10H11NO5
Molecular Weight	225.20 g/mol
Synonyms	1,2,3,4-Tetrahydro-4,6,7-trihydroxy-5-isoquinolinecarboxylic acid; 4,6,7-Trihydroxy-1,2,3,4-tetrahydroisoquinoline-5-carboxylic acid; 5-Carboxy-1,2,3,4-tetrahydro-4,6,7-trihydroxyisoquinoline; Tetrahydrotrihydroxyisoquinolinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Isoquinolinecarboxylic Acid, 1,2,3,4-Tetrahydro-4,6,7-Trihydroxy- (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture uptake and oxidation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.