Description

2-Amino-5,6-Dihydro-4H-Benzothiazol-7-One Hydrobromide is a high-purity organic salt derivative of a benzothiazolone scaffold, serving as a critical advanced pharmaceutical intermediate. This compound matters for its role in the synthesis of novel bioactive molecules, particularly in medicinal chemistry research and development. Pharmaceutical companies and contract research organizations (CROs) specializing in central nervous system (CNS) agents, kinase inhibitors, and other therapeutic areas require this precise building block for lead optimization and process development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead compound optimization.
• Biochemical Reagent: Employed in biochemical assays and as a tool compound for investigating biological mechanisms.
• Organic Synthesis Building Block: Utilized in multi-step synthetic routes for constructing complex heterocyclic molecules.
• Reference Standard: Serves as an analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	2-Amino-5,6-Dihydro-4H-Benzothiazol-7-One Hydrobromide
CAS No.	805250-54-8
Molecular Formula	C7H9N2OS·HBr
Molecular Weight	249.13 g/mol
Synonyms	7H-5,6-Dihydrobenzothiazol-7-one, 2-amino-, hydrobromide; 2-Amino-4,5,6,7-tetrahydro-1,3-benzothiazol-7-one hydrobromide; 2-Amino-5,6-dihydro-4H-1,3-benzothiazol-7-one HBr; 2-Amino-4,5,6,7-tetrahydrobenzothiazol-7-one hydrobromide; 805250-54-8; 2-Amino-5,6-dihydro-4H-benzothiazol-7-one hydrobromide salt
EINECS	Contact for details

Quality Control

Our 2-Amino-5,6-Dihydro-4H-Benzothiazol-7-One Hydrobromide is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development and commercial projects requiring material that meets ICH guidelines for impurities and stability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%; Any single unknown impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.