Description

Ketone, 3-Amino-2-Norbornyl p-Tolyl (8Ci) is a specialized chiral norbornane derivative featuring both amino and ketone functional groups, making it a valuable advanced intermediate for complex organic synthesis. This compound is significant for its rigid, bicyclic structure, which can impart unique stereochemical and conformational properties to target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications such as asymmetric catalysis and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where its structural rigidity can enhance binding specificity and environmental stability.
• Asymmetric Catalyst Ligand Precursor: The amino and ketone groups provide handles for modification into chiral ligands used in enantioselective synthesis.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, including new cycloaddition or functionalization reactions.
• Fine Chemical Synthesis: Employed in the multi-step production of complex fragrance or flavor molecules requiring precise stereochemistry.

Basic Information

Product Name	Ketone, 3-Amino-2-Norbornyl p-Tolyl (8Ci)
CAS No.	802323-68-8
Molecular Formula	C14H17NO
Molecular Weight	215.29 g/mol
Synonyms	3-Amino-2-(4-methylphenyl)norbornan-2-one; 2-Norbornanone, 3-amino-2-(4-methylphenyl)-; 3-Amino-2-(p-tolyl)bicyclo[2.2.1]heptan-2-one; 3-Amino-2-(4-methylphenyl)bicyclo[2.2.1]heptan-2-one; 3-Amino-2-p-tolyl-2-norbornanone; 3-Amino-2-(4-tolyl)norbornan-2-one; (1R,2S,3S,4R)-3-Amino-2-(4-methylphenyl)bicyclo[2.2.1]heptan-2-one (for specific enantiomer).
EINECS	Contact for details

Quality Control

Our Ketone, 3-Amino-2-Norbornyl p-Tolyl (8Ci) is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (or as specified)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.