Description

Bicyclo[5.1.0]Octane-4-Carboxylic Acid, 3,8,8-Trimethyl-5-Oxo-, Methyl Ester, (1R,3R,7S)- (9Ci) is a high-purity, stereochemically defined bicyclic compound that serves as a critical advanced intermediate in complex organic syntheses. Its unique fused ring structure and specific stereochemistry make it an invaluable building block for the development of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals. This product is essential for research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and advanced material sectors who require precise molecular architecture to achieve desired biological activity or material properties.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of novel therapeutic agents, particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where its bicyclic framework contributes to unique modes of action and selectivity.
• Material Science Research: Serves as a precursor for designing monomers and ligands with specific steric and electronic properties for catalysis or polymer applications.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, including catalysis, asymmetric synthesis, and ring-strain reactivity investigations.
• Flavor & Fragrance Industry: Potential use as a starting material for synthesizing complex, high-value odorants and flavor molecules with unique olfactory profiles.

Basic Information

Product Name	Bicyclo[5.1.0]Octane-4-Carboxylic Acid, 3,8,8-Trimethyl-5-Oxo-, Methyl Ester, (1R,3R,7S)- (9Ci)
CAS No.	801222-11-7
Molecular Formula	C14H20O3
Molecular Weight	236.31 g/mol
Synonyms	(1R,3R,7S)-3,8,8-Trimethyl-5-oxobicyclo[5.1.0]octane-4-carboxylic acid methyl ester; Methyl (1R,3R,7S)-3,8,8-trimethyl-5-oxobicyclo[5.1.0]octane-4-carboxylate; Bicyclo[5.1.0]octane-4-carboxylic acid, 3,8,8-trimethyl-5-oxo-, methyl ester, (1R-(1-alpha,3-alpha,7-alpha))-; (1R,3R,7S)-rel-3,8,8-Trimethyl-5-oxobicyclo[5.1.0]octane-4-carboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our production of Bicyclo[5.1.0]Octane-4-Carboxylic Acid, 3,8,8-Trimethyl-5-Oxo-, Methyl Ester, (1R,3R,7S)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized and released according to in-house specifications developed for advanced pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC/GC), chiral purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to prevent moisture absorption and potential contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.