Description

2-Naphthalenemethanol,1,2,3,4,6,7,8,8A-Octahydro-Alpha,Alpha,8,8A-Tetramethyl-,(2R,8R,8Ar)-Rel-(9Ci) is a high-purity, stereochemically defined octahydronaphthalene derivative that serves as a critical chiral intermediate in advanced organic synthesis. Its complex, fused-ring structure with defined stereocenters makes it invaluable for constructing intricate molecular architectures with high precision. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fragrances. The CAS number for this specific stereoisomer is 800385-99-3.

Application

This specialized chiral building block is designed for high-value synthetic applications where stereochemical control is paramount.

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex, stereospecific drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in developing novel, enantiomerically pure pesticides and herbicides with enhanced efficacy and environmental profiles.
• Fragrance & Flavor Chemistry: Serves as a starting material for synthesizing unique, high-value odorants and flavorants with specific sensory characteristics.
• Material Science: Potential monomer or additive for creating advanced polymers with specific chiral or structural properties.
• Academic & Process Chemistry: A valuable tool for methodological development in asymmetric synthesis and catalysis studies.
• Fine Chemical Production: Intermediate for other specialty chemicals requiring a rigid, polycyclic framework.

Basic Information

Item	Details
Product Name	2-Naphthalenemethanol,1,2,3,4,6,7,8,8A-Octahydro-Alpha,Alpha,8,8A-Tetramethyl-,(2R,8R,8Ar)-Rel-(9Ci)
CAS No.	800385-99-3
Molecular Formula	C₁₅H₂₆O
Molecular Weight	222.37 g/mol
Synonyms	(2R,8R,8aR)-1,2,3,4,6,7,8,8a-Octahydro-α,α,8,8a-tetramethyl-2-naphthalenemethanol; rel-(2R,8R,8aR)-Octahydro-α,α,8,8a-tetramethyl-2-naphthalenemethanol; (rel-2R,8R,8aR)-1,2,3,4,6,7,8,8a-Octahydro-α,α,8,8a-tetramethyl-2-naphthalenemethanol; Octahydronaphthalenemethanol derivative; Chiral octahydronaphthalene methanol.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and stereochemical purity. Each lot is characterized using advanced analytical techniques including Chiral HPLC, GC-MS, and NMR spectroscopy to confirm identity, enantiomeric excess (ee), and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor quality documentation to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maximize stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.