Description

Cinchona Calisaya, Ext. is a standardized botanical extract derived from the bark of the *Cinchona calisaya* tree, a primary natural source of alkaloids such as quinine and quinidine. This extract is valued for its consistent bioactive profile, making it a critical starting material and reference standard for high-value applications. It is essential for manufacturers and research institutions in the pharmaceutical, nutraceutical, and fine chemical sectors who require a reliable, high-purity botanical ingredient.

Application

• Pharmaceutical Intermediates: Serves as a key starting material for the synthesis and isolation of quinine and related alkaloids used in antimalarial and antiarrhythmic drugs.
• Reference Standards: Used as a qualitative and quantitative standard in analytical laboratories for HPLC, TLC, and other chromatographic methods.
• Nutraceutical Formulations: Incorporated into dietary supplements and traditional herbal preparations for its historical use and standardized alkaloid content.
• Biochemical Research: Employed in pharmacological studies, receptor binding assays, and as a tool compound in life science research.
• Fine Chemical Synthesis: Provides a natural chiral pool for the semi-synthesis of more complex molecules in organic chemistry.
• Bittering Agent: Used in the food and beverage industry, particularly in the production of tonic water and other bitter flavors.

Basic Information

Product Name	Cinchona Calisaya, Ext.
CAS No.	89997-70-6
Molecular Formula	Complex botanical extract; primary alkaloids include C20H24N2O2 (Quinine)
Molecular Weight	N/A (Extract)
Synonyms	Cinchona Bark Extract; Calisaya Bark Extract; Jesuit's Bark Extract; Peruvian Bark Extract; Quinine Bark Extract; Cinchona succirubra Extract (related); Yellow Cinchona Extract
EINECS	Contact for details

Quality Control

Our Cinchona Calisaya, Ext. is produced under strict quality management protocols. Each batch is tested to confirm identity, purity, and alkaloid content profile using modern analytical techniques. A comprehensive Certificate of Analysis (COA) detailing specifications for key markers such as total alkaloids, quinine content, and residual solvents is provided to ensure traceability and compliance with your requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Fine Brownish Powder
Identification (HPLC/IR)	Conforms to Standard
Assay (Total Alkaloids)	≥ 70% (or as specified)
Quinine Content (HPLC)	Specified Range
Loss on Drying	≤ 5.0%
Residual Solvents (GC)	Meets ICH Guidelines
Heavy Metals	< 10 ppm
Microbial Limits	Meets USP/EP Standards

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.