Description

Digitalis is a purified extract derived from the leaves of the *Digitalis purpurea* (foxglove) plant, containing a mixture of cardiac glycosides. This compound is of critical importance in the pharmaceutical industry as the primary source for the isolation and synthesis of life-saving cardiac medications, such as digoxin and digitoxin. It is essential for manufacturers in the pharmaceutical, biotechnology, and research sectors requiring a reliable, high-purity botanical extract for cardiovascular drug development and production.

Application

• Pharmaceutical Active Ingredient (API): Serves as the key starting material for the isolation and purification of cardiac glycosides like digoxin and digitoxin.
• Cardiovascular Drug Formulation: Used in the research, development, and manufacturing of prescription medications for treating heart failure and certain arrhythmias.
• Biochemical Research: Employed in pharmacological studies to investigate the mechanism of action of cardiac glycosides on sodium-potassium ATPase pumps.
• Reference Standard: Utilized as a certified reference material (CRM) in quality control laboratories for assay calibration and method validation.
• Traditional Medicine Standardization: Acts as a standardized extract for the quality control of herbal preparations where consistent potency is required.

Basic Information

Product Name	Digitalis
CAS No.	1339-93-1
Molecular Formula	Complex mixture; primarily C41H64O13 (Digitoxin) and C41H64O14 (Digoxin)
Molecular Weight	Varies by constituent glycoside (e.g., Digoxin: 780.95 g/mol)
Synonyms	Digitalis Leaf Powder; Foxglove Extract; Digitalis Purpurea Leaf Extract; Digitalis Folium; Digitalis Glycosides; Cardiac Glycoside Mixture; Digilanid
EINECS	215-656-1

Quality Control

Our Digitalis is produced and tested under strict quality management systems to ensure it meets the rigorous standards required for pharmaceutical applications. Each batch is analyzed for key cardiac glycoside content, purity, and biological activity. A comprehensive Certificate of Analysis (COA) is provided, detailing specifications such as assay (HPLC), loss on drying, and microbial limits, ensuring traceability and compliance with cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect potency and stability.

Specification

Item	Specification
Appearance	Fine, greenish-brown to brown powder
Identification (TLC/HPLC)	Conforms to standard
Assay (Total Glycosides)	≥ 95.0% (by HPLC)
Loss on Drying	≤ 5.0%
Ash	≤ 12.0%
Microbial Limits	Meets Ph. Eur./USP requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.