Description

9,10-Dihydroxy-3-Isobutyl-3,4,6,7-Tetrahydro-1H-Pyrido[2,1-A]Isoquinolin-2(11Bh)-One is a complex heterocyclic organic compound with a fused isoquinoline-pyridine structure, serving as a key synthetic intermediate for advanced pharmaceutical research. Its unique molecular scaffold is valued for developing novel bioactive molecules and exploring new chemical entities. This compound is primarily targeted at research and development laboratories in the pharmaceutical and agrochemical sectors, where it is used in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its complex, polycyclic framework.
• Agrochemical Development: Acts as a precursor for novel active ingredients in crop protection research.
• Chemical Biology Probe: Utilized in biochemical assays to study enzyme interactions and receptor binding mechanisms.
• Process Chemistry: Employed in route scouting and scale-up studies for the commercial production of specialty chemicals.
• Academic Research: Used in universities and institutes for synthetic methodology development and heterocyclic chemistry studies.

Basic Information

Product Name	9,10-Dihydroxy-3-Isobutyl-3,4,6,7-Tetrahydro-1H-Pyrido[2,1-A]Isoquinolin-2(11Bh)-One
CAS No.	89929-27-1
Molecular Formula	C18H25NO3
Molecular Weight	303.40 g/mol
Synonyms	9,10-Dihydroxy-3-isobutyl-3,4,6,7-tetrahydro-1H-pyrido[2,1-a]isoquinolin-2(11bH)-one; 3-Isobutyl-9,10-dihydroxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one; 89929-27-1; UNII-9J6H4S8R6S; 9J6H4S8R6S; CHEMBL3183452; SCHEMBL15450299; DTXSID60624269
EINECS	Contact for details

Quality Control

Our 9,10-Dihydroxy-3-Isobutyl-3,4,6,7-Tetrahydro-1H-Pyrido[2,1-A]Isoquinolin-2(11Bh)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and batch-to-batch reproducibility for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep the container tightly sealed in a dry environment to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.