Description

Cyclopropane-2,2,3,3-D4-Carboxylic Acid CAS NO 89924-82-3 is a stable isotope-labeled derivative of cyclopropanecarboxylic acid, where four hydrogen atoms are replaced by deuterium. This high-purity labeled compound is essential for advanced analytical and research applications where precise molecular tracking is required. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors for use as an internal standard, a metabolic tracer, or a building block in the synthesis of deuterated active pharmaceutical ingredients (APIs).

Application

• Internal Standard for Mass Spectrometry (MS): Provides high-accuracy quantification in GC-MS and LC-MS analyses due to its isotopic purity, minimizing matrix effects.
• Metabolic Pathway Tracing: Used in pharmacokinetic and drug metabolism studies to track the fate of molecules in biological systems.
• Deuterated Pharmaceutical Intermediates: Serves as a key precursor in the synthesis of deuterium-labeled drugs, which can offer improved metabolic stability and pharmacokinetic profiles.
• NMR Spectroscopy Solvent & Reagent: Acts as a useful probe or shift reagent in nuclear magnetic resonance (NMR) spectroscopy studies.
• Agrochemical Research: Employed in the development and environmental fate studies of new pesticides and herbicides.
• Academic & Industrial R&D: A critical tool for mechanistic studies in organic chemistry, catalysis, and material science research.

Basic Information

Product Name	Cyclopropane-2,2,3,3-D4-Carboxylic Acid
CAS No.	89924-82-3
Molecular Formula	C4D4H2O2
Molecular Weight	90.11 g/mol
Synonyms	Cyclopropanecarboxylic-2,2,3,3-d4 acid; (2,2,3,3-2H4)Cyclopropanecarboxylic acid; Cyclopropane-D4-carboxylic acid; Deuterated Cyclopropanecarboxylic Acid; Cyclopropanecarboxylic acid-d4; Perdeuterated cyclopropanecarboxylic acid; Cyclopropane-2,2,3,3-tetradeuteriocarboxylic acid
EINECS	Contact for details

Quality Control

Our Cyclopropane-2,2,3,3-D4-Carboxylic Acid is manufactured under strict quality systems to ensure exceptional isotopic and chemical purity, critical for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment (D-atom %), chemical purity (by HPLC/GC), and identity confirmation (by NMR/MS). We adhere to cGMP principles where applicable, and our quality commitment ensures reliable, batch-to-batch consistency for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and potential contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.