Description

Bicyclo[2.1.1]Hexane, 1-(Bromomethyl)- (7Ci,9Ci) is a strained bicyclic organic building block featuring a reactive bromomethyl handle, making it a valuable synthon for advanced organic synthesis. Its unique bridged structure is critical for introducing rigid, three-dimensional geometry into target molecules, which is a key design principle in modern medicinal and materials chemistry. This compound is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those requiring rigid, sp3-rich scaffolds to improve metabolic stability and binding selectivity.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the bicyclo[2.1.1]hexane core can impart favorable physicochemical properties.
• Ligand and Catalyst Development: Employed to construct sophisticated, sterically defined ligands for asymmetric catalysis and organometallic chemistry.
• Polymer & Materials Science: Acts as a monomer or cross-linking agent for creating polymers with unique thermal and mechanical properties due to the strained ring system.
• Chemical Biology Probes: Utilized to synthesize molecular probes and tags that incorporate a rigid linker, useful for studying protein-ligand interactions.
• High-Energy Materials Research: Investigated as a potential building block in the development of advanced propellants and explosives, leveraging its high strain energy.

Basic Information

Product Name	Bicyclo[2.1.1]Hexane, 1-(Bromomethyl)- (7Ci,9Ci)
CAS No.	89892-81-9
Molecular Formula	C7H11Br
Molecular Weight	175.07 g/mol
Synonyms	1-(Bromomethyl)bicyclo[2.1.1]hexane; Bicyclo[2.1.1]hexane-1-methanol, 1-bromo-; 1-Bromomethylbicyclo[2.1.1]hexane; (Bromomethyl)bicyclo[2.1.1]hexane; NSC 406916; Bicyclo[2.1.1]hexylmethyl bromide
EINECS	Contact for details

Quality Control

Our Bicyclo[2.1.1]Hexane, 1-(Bromomethyl)- is produced under strict quality management protocols. Every batch undergoes comprehensive analytical characterization using techniques including GC, HPLC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all relevant specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its highly volatile and light-sensitive nature, containers should be kept sealed and handled under an inert atmosphere when possible to prevent degradation and ensure maximum shelf life.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.