Description

(-)-7-[[(1S)-1,2,4Aα,5,6,7,8,8A-Octahydro-6α-Hydroxy-5,5,8Aβ-Trimethyl-2-Methylenenaphthalene-1β-Yl]Methoxy]-2H-1-Benzopyran-2-One is a high-purity, structurally complex coumarin derivative of significant interest in advanced organic synthesis and pharmaceutical research. Its unique steroidal-like framework makes it a valuable key intermediate for developing novel bioactive molecules. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for its potential in creating new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting hormonal pathways or with steroidal activity.
• Advanced Organic Synthesis: Used as a complex starting material or intermediate in multi-step syntheses for academic and industrial research.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore and optimize biological activity of new chemical entities.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in laboratories.
• Agrochemical Development: Investigated as a precursor for novel plant growth regulators or specialty agrochemicals.
• Biochemical Tool Compound: Utilized in biological assays to study specific enzyme interactions or receptor binding.

Basic Information

Product Name	(-)-7-[[(1S)-1,2,4Aα,5,6,7,8,8A-Octahydro-6α-Hydroxy-5,5,8Aβ-Trimethyl-2-Methylenenaphthalene-1β-Yl]Methoxy]-2H-1-Benzopyran-2-One
CAS No.	89827-12-3
Molecular Formula	C24H30O4
Molecular Weight	382.50 g/mol
Synonyms	7-[(1S,4aS,6R,8aR)-6-Hydroxy-5,5,8a-trimethyl-2-methylidene-3,4,4a,5,6,7,8,8a-octahydro-1H-naphthalen-1-yl]methoxy-2H-chromen-2-one; (6R)-7-[(1S,4aS,6R,8aR)-6-Hydroxy-5,5,8a-trimethyl-2-methylidene-decahydronaphthalen-1-yl]methoxy-chromen-2-one; A ring-substituted coumarin derivative; Light-sensitive coumarin intermediate.
EINECS	Contact for details

Quality Control

Our (-)-7-[[(1S)-1,2,4Aα,5,6,7,8,8A-Octahydro-6α-Hydroxy-5,5,8Aβ-Trimethyl-2-Methylenenaphthalene-1β-Yl]Methoxy]-2H-1-Benzopyran-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.