Description

3-Fluoro-4-Methoxythiophenol is a versatile aromatic thiol derivative, distinguished by its fluorine and methoxy substituents. This compound is a critical building block in advanced organic synthesis, valued for its ability to introduce sulfur-containing functional groups with specific electronic properties. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecules, including active pharmaceutical ingredients (APIs) and specialty polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in sulfur-containing heterocycles and targeted small molecules.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the thiophenol moiety is essential for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands in transition metal catalysis and coordination chemistry.
• Polymer and Material Science: Employed as a monomer or cross-linking agent in the synthesis of high-performance polymers and functional materials.
• Chemical Research: A valuable reagent in academic and industrial laboratories for methodological development and exploring new reaction pathways.
• Fine Chemical Production: Integral to the multi-step synthesis of complex fine chemicals and specialty flavors/fragrances.

Basic Information

Product Name	3-Fluoro-4-Methoxythiophenol
CAS No.	89818-27-9
Molecular Formula	C7H7FOS
Molecular Weight	158.19 g/mol
Synonyms	3-Fluoro-4-methoxybenzenethiol; 4-Methoxy-3-fluorobenzenethiol; 3-Fluoro-4-methoxyphenyl mercaptan; 1-Fluoro-2-methoxy-4-mercaptobenzene; (3-Fluoro-4-methoxyphenyl)thiol; 89818-27-9; 3-Fluoro-p-anisothiol
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-4-Methoxythiophenol is manufactured and tested under strict quality management protocols. We ensure compliance with relevant industry standards for fine chemicals and pharmaceutical intermediates. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed to verify identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee reliable quality and traceability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.