Description

(2-(tert-Butyl)Phenyl)Boronic Acid is a specialized organoboron compound featuring a sterically hindered tert-butyl group adjacent to the boronic acid functionality. This structural motif is critical for its role as a versatile building block in modern synthetic chemistry, particularly in cross-coupling reactions. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, which are prevalent in active pharmaceutical ingredients (APIs) and organic electronic materials.
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, especially those requiring sterically hindered biphenyl scaffolds.
• Agrochemical Synthesis: Employed in creating advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Utilized in the development of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Acts as a handle for bioconjugation and the development of sensors or inhibitors targeting biological pathways.

Basic Information

Product Name	(2-(tert-Butyl)Phenyl)Boronic Acid
CAS No.	89787-13-3
Molecular Formula	C10H15BO2
Molecular Weight	178.04 g/mol
Synonyms	2-(tert-Butyl)benzeneboronic Acid; (2-tert-Butylphenyl)boronic Acid; 2-tert-Butylphenylboronic Acid; B-[2-(1,1-Dimethylethyl)phenyl]boronic Acid; 2-(1,1-Dimethylethyl)benzeneboronic Acid; 2-tert-Butylbenzeneboronic Acid; (2-tert-Butylphenyl)boronic Acid; 2-(tert-Butyl)phenylboronic Acid
EINECS	Contact for details

Quality Control

Our (2-(tert-Butyl)Phenyl)Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.