Description

5Alpha-Androstan-3Alpha-Ol-17-One-16,16-D2 is a high-purity, deuterium-labeled steroid derivative, specifically a deuterated form of androsterone. This compound is of significant value in research and development for its utility as a stable isotope-labeled internal standard in analytical chemistry. It is primarily needed by pharmaceutical research laboratories, contract research organizations (CROs), and academic institutions engaged in advanced metabolic studies, pharmacokinetic research, and the development of sensitive mass spectrometry (MS) and liquid chromatography-mass spectrometry (LC-MS/MS) assays.

Application

• Internal Standard for Bioanalysis: Used as a deuterium-labeled internal standard in quantitative LC-MS/MS methods for the accurate measurement of endogenous steroids or related drug metabolites in biological matrices like plasma, serum, and urine.
• Metabolic Pathway Tracing: Employed in stable isotope tracer studies to investigate androgen metabolism, enzymatic pathways, and steroid hormone dynamics in vitro and in vivo.
• Pharmaceutical R&D: Supports drug discovery and development programs targeting androgen receptors or steroidogenic enzymes, providing a critical tool for assay validation and regulatory submission data.
• Clinical Research: Facilitates the development of high-sensitivity diagnostic assays for endocrine disorders, doping control analysis in sports, and monitoring steroid-related diseases.
• Reference Material: Serves as a certified reference material (CRM) or high-purity chemical standard for calibrating analytical instrumentation and ensuring method accuracy.

Basic Information

Product Name	5Alpha-Androstan-3Alpha-Ol-17-One-16,16-D2
CAS No.	89685-22-3
Molecular Formula	C19H28D2O2
Molecular Weight	292.46 g/mol
Synonyms	Androsterone-16,16-d2; 3α-Hydroxy-5α-androstan-17-one-16,16-d2; 5α-Androstan-3α-ol-17-one-16,16-d2; 16,16-Dideuteroandrosterone; Deuterated Androsterone; 3α-Hydroxy-5α-androstane-17-one-16,16-d2; 5α-Androstane-3α,17β-diol-17-one-16,16-d2 (related); Etiocholan-3α-ol-17-one-16,16-d2
EINECS	Contact for details

Quality Control

Our 5Alpha-Androstan-3Alpha-Ol-17-One-16,16-D2 is manufactured under strict quality control protocols to ensure high chemical purity and isotopic enrichment suitable for analytical applications. Each batch is characterized using advanced techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) is provided, detailing purity, isotopic purity (D-enrichment), and confirming identity. We support compliance with cGMP and ISO 9001 standards for research materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.