Description

2,4-Dimethoxypyrimidine-5-Boronic Acid is a high-purity boronic acid derivative and a key synthetic intermediate in modern organic chemistry. Its value lies in its role as a versatile building block for constructing complex heterocyclic systems via cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, enabling the creation of molecules with specific biological activity.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and bioconjugates for studying biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific pyrimidine derivatives.

Basic Information

Product Name	2,4-Dimethoxypyrimidine-5-Boronic Acid
CAS No.	89641-68-9
Molecular Formula	C6H9BN2O4
Molecular Weight	183.96 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,4-dimethoxypyrimidine; (2,4-Dimethoxypyrimidin-5-yl)boronic acid; 2,4-Dimethoxy-5-pyrimidineboronic acid; 2,4-Dimethoxy-5-pyrimidinylboronic acid; B-(2,4-Dimethoxy-5-pyrimidinyl)boronic acid; 5-Borono-2,4-dimethoxypyrimidine; 89641-68-9
EINECS	Contact for details

Quality Control

Our 2,4-Dimethoxypyrimidine-5-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.