Description

Ethyl 5-Chloro-4-Nitrothiophene-2-Carboxylate is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is needed by research chemists and process development scientists working on novel active ingredients, functional materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or central nervous system disorders.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactive thiophene core.
• Material Science Research: Serves as a building block for creating functional polymers, liquid crystals, or organic semiconductors due to its electron-withdrawing nitro and ester groups.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized colorants and pigments where the thiophene ring contributes to color fastness and unique spectral properties.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and heterocyclic chemistry.

Basic Information

Product Name	Ethyl 5-Chloro-4-Nitrothiophene-2-Carboxylate
CAS No.	89640-03-9
Molecular Formula	C7H6ClNO4S
Molecular Weight	235.64 g/mol
Synonyms	Ethyl 5-chloro-4-nitro-2-thiophenecarboxylate; 2-Thiophenecarboxylic acid, 5-chloro-4-nitro-, ethyl ester; 5-Chloro-4-nitrothiophene-2-carboxylic acid ethyl ester; NSC 406913; Ethyl 5-chloro-4-nitrothiophene-2-carboxylate; 89640-03-9; 5-Chloro-4-nitro-2-thiophenecarboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Chloro-4-Nitrothiophene-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. The container should be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Reported value provided on COA
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.