Description

2-Chloro-8-(Methylthio)-7H-Purine is a versatile purine derivative, a key heterocyclic building block in advanced organic synthesis. This compound matters for its role as a crucial intermediate in the development of nucleoside analogs and other biologically active molecules. Pharmaceutical researchers and fine chemical manufacturers need it for creating potential therapeutic agents, particularly in antiviral and anticancer research.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside and nucleotide analogs for drug discovery programs.
• Antiviral Agent Research: Used in the development of potential antiviral compounds targeting viral polymerases and replication mechanisms.
• Oncology Research: Serves as a building block for creating purine-based molecules studied for their antiproliferative and chemotherapeutic properties.
• Agrochemical Synthesis: Employed in the research and development of new plant growth regulators or pesticides with novel modes of action.
• Biochemical Probe Development: Utilized to create labeled or modified purines for studying enzymatic processes and metabolic pathways.
• Academic & Contract Research: A valuable reagent for universities and CROs conducting fundamental research in medicinal chemistry and heterocyclic chemistry.

Basic Information

Product Name	2-Chloro-8-(Methylthio)-7H-Purine
CAS No.	89581-80-6
Molecular Formula	C₆H₅ClN₄S
Molecular Weight	200.65 g/mol
Synonyms	2-Chloro-8-(methylthio)-7H-purine; 2-Chloro-8-(methylsulfanyl)-7H-purine; 8-(Methylthio)-2-chloropurine; 2-Chloro-8-methylmercaptopurine; 7H-Purine, 2-chloro-8-(methylthio)-; 2-Chloro-8-methylthiopurine; 2-Chloro-8-(methylsulfanyl)purine
EINECS	Contact for details

Quality Control

Our 2-Chloro-8-(Methylthio)-7H-Purine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.