Description

1,3-Thiazole-4-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to act as a versatile sulfonylation reagent, enabling the efficient introduction of the thiazole-4-sulfonyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially those targeting enzymes where sulfonamide groups are pharmacologically active.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides that incorporate heterocyclic sulfonamide structures.
• Material Science Research: Employed in the creation of specialized polymers or functional materials that require sulfonated heterocyclic components.
• Bioconjugation & Probe Development: Useful in biochemical research for labeling proteins or other biomolecules due to its reactive sulfonyl chloride group.
• Fine Chemical Production: Serves as a building block for synthesizing complex, high-value specialty chemicals used in various industrial applications.

Basic Information

Product Name	1,3-Thiazole-4-Sulfonyl Chloride
CAS No.	89501-99-5
Molecular Formula	C3H2ClNO2S2
Molecular Weight	183.64 g/mol
Synonyms	4-Thiazolesulfonyl chloride; Thiazole-4-sulfonyl chloride; 1,3-Thiazol-4-ylsulfonyl chloride; 4-Thiazolesulphonyl chloride; 4-Sulfonylchloridothiazole; Thiazole-4-SO2Cl; 89501-99-5 (CAS)
EINECS	Contact for details

Quality Control

Our 1,3-Thiazole-4-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.