Description

Methyl 4-Amino-5-Bromothiophene-2-Carboxylate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its reactive amino and bromo substituents, which enable precise molecular construction in complex chemical pathways. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of thiophene-based drug candidates, including potential kinase inhibitors and antiviral agents.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the thiophene scaffold for bioactivity.
• Material Science: Serves as a building block for organic semiconductors, conductive polymers, and other electronic materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a versatile scaffold for constructing complex heterocyclic libraries.
• Dye and Pigment Industry: Acts as an intermediate for synthesizing specialized dyes and pigments with unique optical properties.

Basic Information

Product Name	Methyl 4-Amino-5-Bromothiophene-2-Carboxylate
CAS No.	89499-51-4
Molecular Formula	C6H5BrN2O2S
Molecular Weight	249.09 g/mol
Synonyms	Methyl 5-bromo-4-aminothiophene-2-carboxylate; 4-Amino-5-bromothiophene-2-carboxylic acid methyl ester; 5-Bromo-4-aminothiophene-2-carboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 4-amino-5-bromo-, methyl ester; Methyl 4-amino-5-bromo-2-thiophenecarboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 4-Amino-5-Bromothiophene-2-Carboxylate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.