Description

4-Amino-5-Chlorothiophene-2-Carboxylic Acid Methyl Ester is a high-value heterocyclic building block essential for advanced organic synthesis. This compound is a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, offering a versatile scaffold for further functionalization. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Serves as a key building block for developing new-generation herbicides, fungicides, and insecticides.
• Organic Synthesis Reagent: Used in research and development for constructing complex thiophene-containing molecules and heterocyclic compounds.
• Material Science Research: Investigated as a monomer or precursor for conductive polymers and advanced organic electronic materials.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments due to its chromophoric thiophene core.

Basic Information

Product Name	4-Amino-5-Chlorothiophene-2-Carboxylic Acid Methyl Ester
CAS No.	89499-44-5
Molecular Formula	C7H7ClN2O2S
Molecular Weight	218.66 g/mol
Synonyms	Methyl 4-Amino-5-chloro-2-thiophenecarboxylate; 5-Chloro-4-aminothiophene-2-carboxylic acid methyl ester; 4-Amino-5-chloro-2-thiophenecarboxylic acid methyl ester; Methyl 5-chloro-4-aminothiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 4-amino-5-chloro-, methyl ester; 4-Amino-5-chlorothiophene-2-methyl carboxylate
EINECS	Contact for details

Quality Control

Our 4-Amino-5-Chlorothiophene-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and agrochemical applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, containers should be kept in opaque or amber glass, or stored in a dark place.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.