Description

4-Aminothiophene-2-Carboxylic Acid is a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both an amino and a carboxylic acid functional group on a thiophene core, makes it a critical intermediate for constructing complex molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent for creating conductive polymers, organic semiconductors, and advanced polymeric materials.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis and coordination chemistry applications.
• Dye and Pigment Chemistry: Acts as a building block for synthesizing specialized dyes, pigments, and optical brighteners.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and the exploration of new synthetic pathways.

Basic Information

Item	Details
Product Name	4-Aminothiophene-2-Carboxylic Acid
CAS No.	89499-38-7
Molecular Formula	C5H5NO2S
Molecular Weight	143.16 g/mol
Synonyms	2-Carboxy-4-aminothiophene; 4-Amino-2-thiophenecarboxylic acid; 4-Aminothiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 4-amino-; 4-Amino-2-thiophene carboxylic acid; 4-Amino-thiophene-2-carboxylic acid; 4-Aminothiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Every batch of our 4-Aminothiophene-2-Carboxylic Acid is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.