Description

Ethyl 2-(Trifluoromethyl)-1H-1,3-Benzodiazole-5-Carboxylate is a high-value fluorinated benzimidazole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in the trifluoromethyl group, which imparts desirable properties like enhanced metabolic stability and lipophilicity to final compounds. This product is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in oncology, antiviral, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity.
• Material Science Research: Serves as a precursor for specialty chemicals, dyes, and functional materials requiring fluorinated heterocyclic cores.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions and as a ligand precursor in catalytic systems.
• Academic & R&D Laboratories: A valuable reagent for methodological studies and exploring new chemical spaces in fluorinated chemistry.

Basic Information

Product Name	Ethyl 2-(Trifluoromethyl)-1H-1,3-Benzodiazole-5-Carboxylate
CAS No.	89457-09-0
Molecular Formula	C11H9F3N2O2
Molecular Weight	258.20 g/mol
Synonyms	5-Carbethoxy-2-trifluoromethylbenzimidazole; Ethyl 5-Benzimidazolecarboxylate, 2-(Trifluoromethyl)-; 2-(Trifluoromethyl)-1H-benzimidazole-5-carboxylic acid ethyl ester; 1H-Benzimidazole-5-carboxylic acid, 2-(trifluoromethyl)-, ethyl ester; Ethyl 2-(trifluoromethyl)-1H-benzo[d]imidazole-5-carboxylate; 89457-09-0; 2-Trifluoromethyl-5-ethoxycarbonylbenzimidazole
EINECS	Contact for details

Quality Control

Our Ethyl 2-(Trifluoromethyl)-1H-1,3-Benzodiazole-5-Carboxylate is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the stringent requirements for pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.