Description

4-Fluoroindole-3-Acetonitrile is a versatile fluorinated indole derivative, a key synthetic intermediate prized for its reactive nitrile and indole functionalities. This compound is essential for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily utilized in the synthesis of complex heterocyclic compounds, serving the pharmaceutical, agrochemical, and advanced materials research sectors.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of fluorinated tryptamine analogs, serotonin receptor modulators, and other bioactive indole-based molecules.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and plant growth regulators that leverage the fluorinated indole scaffold for enhanced activity and stability.
• Organic Synthesis: Serves as a versatile precursor for constructing complex heterocyclic frameworks via reactions at the nitrile and indole positions.
• Biochemical Research: Employed in the study of enzyme inhibitors and as a probe molecule in medicinal chemistry programs targeting neurological pathways.
• Material Science: Potential intermediate for synthesizing specialty polymers and organic electronic materials containing fluorinated aromatic units.

Basic Information

Product Name	4-Fluoroindole-3-Acetonitrile
CAS No.	89434-04-8
Molecular Formula	C10H7FN2
Molecular Weight	174.18 g/mol
Synonyms	4-Fluoro-1H-indole-3-acetonitrile; 3-(Cyanomethyl)-4-fluoro-1H-indole; 4-Fluoroindol-3-ylacetonitrile; (4-Fluoro-1H-indol-3-yl)acetonitrile; 4-Fluoro-3-indoleacetonitrile; 4-Fluoroindole-3-acetic acid nitrile; 89434-04-8; 4-Fluoroindole-3-cyanomethane
EINECS	Contact for details

Quality Control

Our 4-Fluoroindole-3-Acetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.