Description

Methyl 3-Hydroxy-5-Nitro-2-Thiophenecarboxylate is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), specialty dyes, and novel materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those with thiophene-based scaffolds targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its nitro and ester functionalities.
• Material Science Research: Serves as a building block for creating functional organic materials, such as organic semiconductors or conductive polymers.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing specialized heterocyclic dyes and colorants.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including cross-coupling and heterocyclic chemistry.
• Custom Synthesis Projects: Supplied for contract research organizations (CROs) and CDMOs engaged in bespoke chemical synthesis for clients.

Basic Information

Product Name	Methyl 3-Hydroxy-5-Nitro-2-Thiophenecarboxylate
CAS No.	89380-77-8
Molecular Formula	C7H5NO5S
Molecular Weight	215.18 g/mol
Synonyms	Methyl 5-nitro-3-hydroxy-2-thiophenecarboxylate; 3-Hydroxy-5-nitro-2-thiophenecarboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 3-hydroxy-5-nitro-, methyl ester; Methyl 3-hydroxy-5-nitrothiophene-2-carboxylate; 5-Nitro-3-hydroxythiophene-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Hydroxy-5-Nitro-2-Thiophenecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle and store the material under an inert atmosphere for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.