Description

1-(3-Iodothiophen-2-Yl)Ethanone is a high-purity iodinated thiophene derivative, a key building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the life sciences and specialty chemical industries for constructing novel heterocyclic compounds and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing functionalized thiophene scaffolds.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides where the iodothiophene moiety imparts specific biological activity.
• Material Science: Serves as a monomer or building block for creating conjugated polymers and organic electronic materials for applications in OLEDs and sensors.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form complex biaryl systems.
• Chemical Research & Development: A valuable tool for medicinal chemists exploring structure-activity relationships (SAR) and for synthesizing libraries of novel heterocyclic compounds.

Basic Information

Product Name	1-(3-Iodothiophen-2-Yl)Ethanone
CAS No.	89380-60-9
Molecular Formula	C6H5IOS
Molecular Weight	252.07 g/mol
Synonyms	2-Acetyl-3-iodothiophene; 3-Iodo-2-acetylthiophene; Ethanone, 1-(3-iodo-2-thienyl)-; 1-(3-Iodothiophen-2-yl)ethan-1-one; 3-Iodothiophene-2-carbaldehyde, methyl ketone derivative
EINECS	Contact for details

Quality Control

Our 1-(3-Iodothiophen-2-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.