Description

tert-Butyl 3-Methyl-1H-Indole-1-Carboxylate is a protected indole derivative that serves as a versatile and critical building block in advanced organic synthesis. This compound is essential for pharmaceutical research and development, enabling the controlled functionalization of the indole scaffold. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of complex molecules and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides that leverage the indole core structure.
• Organic Synthesis Building Block: The tert-butoxycarbonyl (Boc) protecting group allows for selective reactions on the indole nitrogen, facilitating multi-step synthetic routes.
• Material Science Research: Serves as a monomer or precursor for the development of specialty polymers and advanced organic materials.
• Academic & Contract Research: Employed in university laboratories and CROs (Contract Research Organizations) for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	tert-Butyl 3-Methyl-1H-Indole-1-Carboxylate
CAS No.	89378-43-8
Molecular Formula	C14H17NO2
Molecular Weight	231.29 g/mol
Synonyms	1H-Indole-1-carboxylic acid, 3-methyl-, 1,1-dimethylethyl ester; 3-Methyl-1H-indole-1-carboxylic acid tert-butyl ester; 1-Boc-3-methylindole; tert-Butyl 3-methylindole-1-carboxylate; Boc-3-methylindole; 89378-43-8; 1-(tert-Butoxycarbonyl)-3-methylindole
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Methyl-1H-Indole-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.