Description

1-(4-Bromobutyl)-4-Fluorobenzene is a versatile bifunctional organic building block containing both a reactive bromoalkyl chain and a fluorinated aromatic ring. This compound is valued for its role as a key intermediate in the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical and life science industries for constructing target compounds through nucleophilic substitution and cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a fluorobenzyl or phenalkyl moiety.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic semiconductors and liquid crystal compounds.
• Cross-Coupling Reactions: The bromobutyl side chain is amenable to various palladium-catalyzed reactions (e.g., Suzuki, Heck) for carbon-carbon bond formation.
• Ligand & Catalyst Preparation: Utilized in the synthesis of specialized phosphine or nitrogen-based ligands for catalysis.
• Polymer Modification: Acts as a functional monomer or modifier to introduce fluorine and reactive alkyl halide groups into polymer chains.

Basic Information

Product Name	1-(4-Bromobutyl)-4-Fluorobenzene
CAS No.	89326-70-5
Molecular Formula	C10H12BrF
Molecular Weight	231.11 g/mol
Synonyms	4-(4-Bromobutyl)fluorobenzene; 1-Bromo-4-(4-fluorophenyl)butane; p-Fluorophenylbutyl bromide; 4-Fluorobenzylbutyl bromide; 4'-Fluoro-1-phenyl-4-bromobutane; (4-Bromobutyl)fluorobenzene; 4-Fluorophenylbutyl bromide
EINECS	Contact for details

Quality Control

Our production of 1-(4-Bromobutyl)-4-Fluorobenzene adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including GC, HPLC, and NMR for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment, supporting your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.