Description

5-Bromo-4-Nitrothiophene-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring bromo and nitro substituents on a thiophene carboxylic acid core, makes it a critical intermediate for constructing complex molecules with tailored electronic and biological properties. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications in drug discovery, crop protection, and functional polymer development.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting infectious diseases and central nervous system disorders.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its reactive halogen and nitro groups.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of conductive polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Ligand and Catalyst Development: Employed to create novel chelating ligands and organocatalysts for asymmetric synthesis and transition metal catalysis.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments where the thiophene ring contributes to color fastness and unique chromatic properties.

Basic Information

Product Name	5-Bromo-4-Nitrothiophene-2-Carboxylic Acid
CAS No.	89283-24-9
Molecular Formula	C5H2BrNO4S
Molecular Weight	251.04 g/mol
Synonyms	5-Bromo-4-nitro-2-thiophenecarboxylic acid; 2-Thiophenecarboxylic acid, 5-bromo-4-nitro-; 4-Nitro-5-bromothiophene-2-carboxylic acid; 5-Bromo-4-nitrothiophene-2-carboxylate; BNTC; 89283-24-9 (CAS); 5-Br-4-NO2-Thiophene-2-COOH
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-4-Nitrothiophene-2-Carboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of your synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot and supplied with every order.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.