Description

Methyl 4,5-Dichlorothiophene-2-Carboxylate is a high-purity, versatile heterocyclic building block and key synthetic intermediate. This compound is valued for its role in constructing complex molecular architectures, particularly in advanced pharmaceutical and agrochemical research. It is essential for chemists and manufacturers in the fine chemical, pharmaceutical, and material science industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the thiophene scaffold for enhanced bioactivity.
• Material Science Research: Serves as a monomer or building block for creating conjugated polymers and organic electronic materials like OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organocatalysts.
• Chemical Biology Probes: Utilized as a core structure for designing molecular probes and fluorescent tags for biological imaging and diagnostic applications.
• Custom Synthesis and R&D: A fundamental starting material for contract research organizations (CROs) and academic laboratories engaged in heterocyclic chemistry and medicinal chemistry projects.

Basic Information

Item	Details
Product Name	Methyl 4,5-Dichlorothiophene-2-Carboxylate
CAS No.	89281-29-8
Molecular Formula	C7H4Cl2O2S
Molecular Weight	223.08 g/mol
Synonyms	Methyl 4,5-dichloro-2-thiophenecarboxylate; 4,5-Dichlorothiophene-2-carboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 4,5-dichloro-, methyl ester; Methyl 4,5-dichlorothiophene-2-carboxylate; 4,5-Dichloro-2-(methoxycarbonyl)thiophene; Methyl 4,5-dichloro-2-thiophenecarboxylate
EINECS	Contact for details

Quality Control

Our Methyl 4,5-Dichlorothiophene-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent lot-to-lot performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.